N-Heterocyclic Carbene-Catalyzed C–H Heteroarylation of Aldehydes for the Rapid Synthesis of Aryl Heteroaryl Ketones

Mukhopadhyay, S.; Pal, A.; Barik, S.; Biju, A. T.

Org. Lett. 2026 , 28 , 8357-8363. View paper

Base-Mediated (3+3) Annulation of Bicyclo[1.1.0]butanes with Diarylmethyl Isothiocyanates for Access to 3-Azabicyclo[3.1.1]heptanes.

Roy, P.; Biju, A. T.

Org. Lett. 2026 , 28 , 8350-8356. View paper

Lewis Acid-Catalyzed (3+3) Annulation of Bicyclo[1.1.0]butanes with Mercaptoacetaldehyde: Access to 2-Thiabicyclo[3.1.1]heptanes.

Pal, A.; Roy, P.; Shrotriya, S.; Biju, A. T.

Org. Lett. 2026 , 28 , 7247-7253. View paper

Access to C-N and N-N Axially Chiral Pyridinones via NHC-Catalyzed Dynamic Kinetic Resolution of Rotationally Restricted Cyclic Imides.

Ranganathappa, S. S.; Das, A.; Biju, A. T.

Angew. Chem. Int. Ed. 2026 , 65 , e3289722. View paper

Temperature-Controlled Divergent Reactions of Bicyclo[1.1.0]butanes with Thiocyanate-based Protic Ionic Liquids.

Roy, P.; Das, R. C.; Biju, A. T.

Green. Chem 2026 , 28 , 8593-8603. View paper

Strain-Release Pudovik Reaction Enabled Diastereodivergent Hydroxy Transfer to Bicyclo[1.1.0]butanes Using Diphenyl Phosphine Oxide.

Das, R. C.; Roy, P.; Biju, A. T.

ACS Catal 2026 , 16 , 8174-8187. View paper

Enantioselective Synthesis of P(V)-Stereogenic Phosphacycles by NHC-Catalyzed Desymmetric Annulation.

Barik, S.; Mukhopadhyay, S; Gogoi, R.; Biju, A. T.

ChemRxiv 2026 , 00 , Preprint. View paper

Recent Advances in the Strain-Release Driven Reactions of Bicyclobutanes: An Emerging Landscape in Organic Synthesis.

Deswal, S.; Das, R. C.; Biju, A. T.

Chem. Soc. Rev. 2026 , 55 , 5572-5589. View paper

N-Heterocyclic Carbene-Catalyzed (3 + 3) Annulation for the Diastereo- and Atroposelective Synthesis of N–N Axially Chiral Quino(xa)linones.

Ranganathappa, S. S.; Radhakrishnan, K. K.; Paravakkal, F. D.; Biju, A. T.

ACS Sustainable Chem. Eng. 2026 , 14 , 5238-5247. View paper

HFIP-Mediated (3+2) Annulation of Bicyclobutanes with Indolyl Alcohols for Diastereoselective Access to Tetracyclic Spiroindolenines.

Deswal, S.; Biju, A. T.

Org. Lett. 2026 , 28 , 1392-1398. View paper

Lewis Acid-Assisted Formal C═S Insertion of Thioindolinones to Bicyclobutanes: Diastereoselective Access to Trisubstituted Cyclobutanethiols.

Roy, P.; Deswal, S.; Biju, A. T.

Org. Lett. 2025 , 27 , 10916-10922. View paper

HFIP-Mediated Ring-Opening of Bicyclo[1.1.0]butanes with Hydroperoxides for the Diastereoselective Access to Peroxycyclobutanes.

Gupta, P.; Roy, P.; Biju, A. T.

Org. Lett. 2025 , 27 , 10477-10483. View paper

HFIP-Mediated Spiro-annulation of Bicyclo[1.1.0]butanes with α-Halo Hydroxamates: Access to Functionalized Spirocyclobutenes.

Shajahan, S.; Deswal, S.; George, M.; Ahmad, M.; Mohanan, K.; Werz, D. B.; Biju, A. T.

Org. Lett. 2025 , 27 , 8137-8143. View paper

Ruthenium(II)-Catalyzed Annulation of Vinyl Sulfoxonium Ylides with Arynes for the Rapid Synthesis of Functionalized 1-Naphthols.

Shrotriya, S.; Paravakkal, F. D.; Biju, A. T.

Org. Lett. 2025 , 27 , 8131-8136. View paper

Dynamic Kinetic Resolution Approach to C-O Axially Chiral Benzonitriles via NHC-Catalyzed Atroposelective Imine Umpolung.

Shee, S.; Ramachandran, D.; Gogoi, R.; Biju, A. T.

ACS Catal 2025 , 15 , 13157-13166. View paper

Control Over S(VI)-Stereogenic Center: NHC-Catalyzed Enantioselective Synthesis of N-Acyl Cyclic Sulfonimidamides.

Barik, S.; Paravakkal, F. D.; Gupta, P.; Roy, P.; Biju, A. T.

Angew. Chem. Int. Ed. 2025 , 64 , e202506929. View paper

Simultaneous Activation of Bicyclobutanes and Indolyl Alcohols Using HFIP: Access to Indole-Fused Bicyclo[3.1.1]heptanes.

Deswal, S.; Das, R. C.; Sarkar, D.; Biju, A. T.

Angew. Chem. Int. Ed. 2025 , 64 , e202501655. View paper

N-Heterocyclic Carbene-Catalyzed Imine Umpolung for the Cross-Coupling of Quinoxalin-2-ones with Isatins.

Barik, S.; Kunhiraman, A. A.; Das, R. C.; Biju, A. T.

JACS Au 2025 , 5 , 948-954. View paper

Lewis Acid-Catalyzed 1,3-Dipolar Cycloaddition of Bicyclobutanes with Isatogens: Access to Indoxyl-Fused Bicyclo[3.1.1]heptanes.

Deswal, S.; Das, R. C.; Sarkar, D.; Biju, A. T.

JACS Au 2025 , 5 , 136-143. View paper

N-Heterocyclic Carbene (NHC) Organocatalysis: From Fundamentals to Frontiers.

Chakraborty, S.; Barik, S.; Biju, A. T.

Chem. Soc. Rev. 2025 , 54 , 1102-1124. View paper

Electroredox N-Heterocyclic Carbene-Catalyzed Enantioselective (3+3) Annulation of Enals with 2-Naphthols.

Kale, V.; Shee, S.; Dutt, S.; Sinha, N.; Biju, A. T.; Banerjee, P.

Org. Lett. 2025 , 27 , 57-62. View paper

NHC-Catalyzed Aldimine Umpolung/6π-Electrocyclization Cascade to Access Tetracyclic Dihydrochromeno Indoles.

Das, R. C.; Gupta, P.; Chakraborty, S.; Jindal, G.; Biju, A. T.

Angew. Chem. Int. Ed. 2025 , 64 , e202416519. View paper

Access to β-Keto Amino Acid Derivatives via Interrupted Polonovski Strategy Involving NHC-Catalyzed Aza Benzoin Reaction.

Dehury, B. S.; Barik, S.; Sankar, G.; Biju, A. T.

Org. Lett. 2024 , 26 , 10690-10695. View paper

Birth of Organocatalysis by N-Heterocyclic Carbenes.

Chakraborty, S.; Biju, A. T.

Nat. Catal. 2024 , 7 , 1060-1062. Invited Retro News & Views. View paper

Lewis Acid-Catalyzed (3+2) Annulation of Bicyclobutanes with Ynamides: Access to 2-Amino Bicyclo[2.1.1]hexenes.

Sarkar, D.; Deswal, S.; Das, R. C.; Biju, A. T.

Chem. Sci. 2024 , 15 , 16243-16249. View paper

Lewis Acid-Catalyzed Unusual (4+3) Annulation of para-Quinone Methides with Bicyclobutanes: Access to Oxabicyclo [4.1.1]octanes.

Deswal, S.; Guin, A.; Biju, A. T.

Angew. Chem. Int. Ed. 2024 , 63 , e202408610. View paper

Atroposelective Synthesis of N-Aryl Phthalimides and Maleimides via NHC-Catalyzed Activation of Carboxylic Acids.

Barik, S.; Ranganathappa, S. S.; Biju, A. T.

Nat. Commun. 2024 , 15 , 5755. View paper

Lewis Acid-Catalyzed Diastereoselective Formal Ene Reaction of Thioindolinones/Thiolactams with Bicyclobutanes.

Guin, A.; Deswal, S.; Harariya, M. S.; Biju, A. T.

Chem. Sci. 2024 , 15 , 12473-12479. View paper

Atroposelective Synthesis of N–N Axially Chiral Indoles and Pyrroles via NHC-Catalyzed Diastereoselective (3 + 3) Annulation Strategy.

Ranganathappa, S. S.; Dehury, B, S.; Singh, G. K.; Shee, S.; Biju, A. T.

ACS Catal 2024 , 14 , 6965–6972. View paper

N-Heterocyclic Carbene-Catalyzed Imine Umpolung/Semipinacol Rearrangement Cascade for the Synthesis of Indoxyls.

Das, R. C.; Barik, S.; Kunhiraman, A. A.; Goswami, A.; Mondal, A.; De, M.; Biju, A. T.

ACS Catal 2024 , 14 , 4202–4210. View paper

Enantioselective Synthesis of Tricyclic Oxoquinolines via NHC-Catalyzed Michael-Aldol-Lactamization-Dehydration Cascade.

Barik, S.; Sankar, G.; Biju, A. T.

Chem. Commun. 2024 , 60 , 4290-4293. Highlighted in the front cover. View paper

Lewis Acid-Catalyzed One-Pot Thioalkenylation of Donor-Acceptor Cyclopropanes Using in situ Generated Dithiocarbamates and Propiolates.

Harikumar, S.; Kandy, L. T. K.; Guin, A.; Biju, A. T.

Org. Biomol. Chem. 2024 , 22 , 1834-1838. Invited to the special issue celebrating the 100th birthday of Prof. Sukh Dev.. View paper

Stereoselective Alder-ene Reactions of Bicyclo[1.1.0]butanes: Facile Synthesis of Cyclopropyl- and Aryl-substituted Cyclobutenes.

Dasgupta, A.; Bhattacharjee, S.; Tong, Z.; Guin, A.; McNamee, R.; Christensen, K.; Biju, A. T.; Anderson, E.

J. Am. Chem. Soc. 2024 , 146 , 1196-1203. View paper

Ring-Opening 1,3-Difunctionalization of Donor-Acceptor Cyclopropanes.

Guin, A.; Biju, A. T.

In “Donor-Acceptor Cyclopropanes in Organic Synthesis“ 2024 , Chapter 6 , Editors: P. Banerjee and A. T. Biju; Wiley-VCH. 2024, ISBN: 978-3-527-349876. View paper

Enantioselective Synthesis of C-O Axially Chiral Diaryl Ethers via NHC-Catalyzed Atroposelective Desymmetrization.

Shee, S.; Ranganathappa, S. S.; Gadhave, M. S.; Gogoi, R.; Biju, A. T.

Angew. Chem. Int. Ed. 2023 , 62 , e202311709. View paper

Nucleophilic Acylation-Annulation Cascade of 2-Chlorobenzonitriles using Aldehydes Triggered by N-Heterocyclic Carbenes.

Gadhave, M. S.; Barik, S.; Wessels, F.; Biju, A. T.

Org. Lett. 2023 , 25 , 8314–8319. View paper

NHC-Catalyzed Enantioselective Synthesis of Tetracyclic δ-Lactones by (4 + 2) Annulation of ortho-Quinodimethanes with Activated Ketones.

Sarkar, D.; Barik, S.; Shee, S.; Biju, A. T.

Org. Lett. 2023 , 25 , 7852-7857. View paper

N-Heterocyclic Carbene-Catalyzed Atroposelective Synthesis of N-N Axially Chiral 3-Amino Quinazolinones.

Balanna, K.; Barik, S.; Barik, S.; Shee, S.; Manoj, N.; Gonnade, R. G.; Biju, A. T.

ACS Catal 2023 , 13 , 8752-8759. View paper

Lewis Acid-Catalyzed Diastereoselective Carbofunctionalization of Bicyclobutanes Employing Naphthols.

Guin, A.; Bhattacharjee, S.; Harariya, M. S.; Biju, A. T.

Chem. Sci. 2023 , 14 , 6585-6591. View paper

Benzotriazole-Triggered Three-Component Lewis Acid-Catalyzed Ring-Opening 1,3-Aminofunctionalization of Donor-Acceptor Cyclopropanes.

Deswal, S.; Guin, A.; Biju, A. T.

Org. Lett. 2023 , 25 , 1643-1648. View paper

Directing Group-Free Regioselective meta-C-H Functionalization of Pyridines.

Chakraborty, S.; Biju, A. T.

Angew. Chem. Int. Ed. 2023 , 62 , e202300049. View paper

N-Heterocyclic Carbene-Catalyzed aza-Michael-Mannich-Lactamization Cascade for the Enantioselective Synthesis of Pyrazoloquinolin-3-ones.

Shee, S.; Sarkar, D.; Biju, A. T.

Org. Lett. 2023 , 25 , 220-225. View paper

Enantioselective Synthesis of Dihydrothiopyranones via NHC-Catalyzed [3+3] Annulation of 2-Bromoenals with β-Oxodithioesters.

Barik, S.; Shee, S.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2022 , 24 , 8848-8853. View paper

Dynamic Kinetic Resolution of γ,γ-Disubstituted Indole 2-Carboxaldehydes via NHC-Lewis Acid Cooperative Catalysis for the Synthesis of Tetracyclic ε-Lactones.

Balanna, K.; Barik, S.; Shee, S.; Gonnade, R. G.; Biju, A. T.

Chem. Sci. 2022 , 13 , 11513-11518. Among the 2022 Chem. Sci. Pick of the Week Collection and 2022 Chem. Sci. HOT Article Collection.. View paper

N-Heterocyclic Carbene-Catalyzed Umpolung of Cyclopent-4-ene-1,3-diones for Activated Olefin–Isatin Cross-Coupling.

Barik, S.; Shee, S.; Biju, A. T.

Org. Lett. 2022 , 24 , 6066-6071. View paper

Kinetic Resolution Approach to the Synthesis of C-N Axially Chiral N-Aryl Aminomaleimides via NHC-Catalyzed [3+3] Annulation.

Barik, S.; Das, R. C.; Balanna, K.; Biju, A. T.

Org. Lett. 2022 , 24 , 5456-5461. View paper

Synthesis of Trisubstituted Oxazoles via Aryne Induced [2,3] Sigmatropic Rearrangement-Annulation Cascade.

Gaykar, R. N.; Deswal, S.; Guin, A.; Bhattacharjee, S.; Biju, A. T.

Org. Lett. 2022 , 24 , 4145-4150. View paper

N-Heterocyclic Carbene (NHC)-Catalyzed Transformations Involving Azolium Enolates.

Mondal, S.; Ghosh, A.; Biju, A. T.

Chem. Rec. 2022 , 22 , e202200054. View paper

Ring-Opening 1,3-Carbothiolation of Donor-Acceptor Cyclopropanes Using Alkyl Halides and in Situ Generated Dithiocarbamates.

Guin, A.; Deswal, S.; Biju, A. T.

J. Org. Chem. 2022 , 87 , 6504-6513. View paper

A Benzannulation Strategy for Rapid Access to Quinazoline-2,4-diones via Oxidative N-Heterocyclic Carbene Catalysis.

Ghosh, A.; Shee, S.; Biju, A. T.

Org. Lett. 2022 , 24 , 2772-2777. View paper

Organocatalytic Routes to C-H Functionalization Reactions.

Barik, S.; Biju, A. T.

In “Handbook of C-H Functionalization (CHF)“, Editor: D. Maiti 2022 , Wiley-VCH , 1-39. View paper

Umpolung Organocatalytic Strategies – Beyond Classical Reactivity Patterns.

Shee, S.; Ghosh, A.; Biju, A. T.

In “Asymmetric Organocatalysis: New Strategies, and Opportunities“, Chapter 22, Editors: L. Albrecht, A. Albrecht, L. Dell’Amico 2022 , Wiley-VCH , 497-537. View paper

Aryne Three-Component Coupling Involving CS2 for the Synthesis of S-Aryl Dithiocarbamates.

Bhattacharjee, S.; Deswal, S.; Manoj, N.; Jindal, G.; Biju, A. T.

Org. Lett. 2021 , 23 , 9083-9088. View paper

Synthesis of Functionalized Dihydrocoumarins by NHC-Catalyzed [3+3] Annulation of Enals with 2-Substituted Naphthoquinones.

Shee, S.; Barik, S.; Ghosh, A.; Biju, A. T.

Org. Lett. 2021 , 23 , 8039-8044. View paper

Three-Component, Diastereoselective [6+3] Annulation of Tropone, Imino Esters and Arynes.

Guin, A.; Gaykar, R. N.; Deswal, S.; Biju, A. T.

Org. Lett. 2021 , 23 , 7456-7461. View paper

Transition-Metal-Free C2-Functionalization of Pyridines through Aryne Three-Component Coupling.

Guin, A.; Bhattacharjee, S.; Biju, A. T.

Chem. Eur. J. 2021 , 27 , 13864-13869. Selected as a “Hot Paper” by the Editors. View paper

Enantioselective Synthesis of Tetra-substituted Tetralines and Tetra-hydroindolizines via NHC-Catalyzed Azolium-Enolate Cascade.

Ghosh, A.; Barik, S.; Shee, S.; Biju, A. T.

Chem. Commun. 2021 , 57 , 7794-7797. View paper

Oxidative N-Heterocyclic Carbene (NHC) Catalysis for the Rapid Access to Functionalized Pyrrolo-oxazinones.

Ghosh, A.; Barik, S.; Barik, S.; Shee, S.; Biju, A. T.

Tetrahedron. 2021 , 94 , 132330. Invited to the Special issue on System-Oriented Development of Organocatalysis. View paper

Enantioselective Synthesis of 5,6-Dihydroindolizines by N‑Heterocyclic Carbene (NHC)-Catalyzed Core-Structure-Inspired Strategy of Azolium-Enolate Cascade

Ghosh, A.; Shee, S.; Barik, S.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2021 , 23 , 5223-5228. View paper

An Umpolung Oxa-[2,3] Sigmatropic Rearrangement Employing Arynes for the Synthesis of Functionalized Enol Ethers.

Gaykar, R. N.; George, M.; Guin, A.; Bhattacharjee, S.; Biju, A. T.

Org. Lett. 2021 , 23 , 3447-3452. View paper

NHC-Catalyzed Desymmetrization of N-Aryl Maleimides Leading to the Atroposelective Synthesis of N-Aryl Succinimides.

Barik, S.; Shee, S.; Das, S.; Gonnade, R. G.; Jindal, G.; Mukherjee, S.; Biju, A. T.

Angew. Chem. Int. Ed. 2021 , 60 , 12264-12268. This article appears in ‘HOT Topic’: Organocatalysis; Highlighted in Synfacts 2021, 17, 691. View paper

Revealing the Similarities of α,β-Unsaturated Iminiums and Acylazoliums in Organocatalysis.

Ghosh, A.; Biju, A. T.

Angew. Chem. Int. Ed. 2021 , 60 , 13712-13724. This article appears in ‘HOT Topic’: Organocatalysis. View paper

Molecular Rearrangements via Aryne Intermediates.

Guin, A.; Deswal, S.; Biju, A. T.

In Comprehensive Aryne Synthetic Chemistry 2021 , Chapter 2.4 , ELSEVIER SCIENCE, 2021, 223-266. View paper

Hetarynes, Cyclohexynes and Related Chemistry.

Guin, A.; Bhattacherjee, S.; Biju, A. T.

In Modern Aryne Chemistry, Wiley-VCH, Chapter 9, 2021 , Editor: A. T. Biju, ISBN 978-3-527-34646-2 , pages 359-406. View paper

Introduction to the Chemistry of Arynes.

Roy, T.; Guin, A.; Biju, A. T.

In Modern Aryne Chemistry. Wiley-VCH, Chapter 1, 2021 , Editor: A. T. Biju, ISBN 978-3-527-34646-2 , pages 1-25. View paper

Employing Arynes in Transition-Metal-Free Synthesis of Benzo-Fused Five and Six-Membered Heterocycles: An Update.

Roy, T.; Biju, A. T.

In Green Synthetic Approaches for Biologically Relevant Heterocycles 2021 , ELSEVIER SCIENCE, 2021, , pages 355-382. View paper

N-Heterocyclic Carbene (NHC) Organocatalysis Using Aliphatic Aldehydes.

Barik, S.; Biju, A. T.

Chem. Commun. 2020 , 56 , 15484-15495. View paper

Thiophenols as Protic Nucleophilic Triggers in Aryne Three-Component Coupling.

Bhattacherjee, S.; Guin, A.; Gaykar, R. N.; Biju, A. T.

Org. Lett. 2020 , 22 , 9097-9101. View paper

Enantioselective Synthesis of Tricyclic β‑Lactones by NHC-Catalyzed Desymmetrization of Cyclic 1,3-Diketones.

Shee, S.; Mukherjee, S.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2020 , 22 , 5407-5411. View paper

Imines as Acceptors and Donors in N-Heterocyclic Carbene (NHC) Organocatalysis.

Das, T. K.; Biju, A. T.

Chem. Commun. 2020 , 56 , 8537- 8552, Selected as a “HOT Article” by Editor & Referees of Chem. Commun.. View paper

Rapid Synthesis of Zwitterionic Phosphonium Benzoates by a Three‐Component Coupling Involving Phosphines, Arynes and CO2.

Bhattacharjee, S.; Raju, A.; Gaykar, R. N.; Gonnade, R. G.; Roy, T.; Biju, A. T.

Chem. Asian J. 2020 , 15 , 2203-2207. View paper

Catalytic, Enantioselective C2-Functionalization of 3-Aminobenzofurans Using N-Heterocyclic Carbenes.

Barik, S.; Shee, S.; Ghosh, A.; Biju, A. T.

Org. Lett. 2020 , 22 , 3865-3869. View paper

N-Heterocyclic Carbene Catalysis Exploiting Oxidative Imine Umpolung for the Generation of Imidoyl Azoliums.

Das, T. K.; Madica, K.; Krishnan, J.; Marelli, U. K.; Biju, A. T.

J. Org. Chem. 2020 , 85 , 5114-5121. View paper

Lewis Acid-Catalyzed Ring-Opening 1,3-Aminothiolation of Donor-Acceptor Cyclopropanes Using Sulfenamides.

Guin, A.; Rathod, T.; Gaykar, R. N.; Roy, T.; Biju, A. T.

Org. Lett. 2020 , 22 , 2276-2280. View paper

N‐Heterocyclic Carbene‐Catalyzed Formal [6+2] Annulation Reaction via Cross‐Conjugated Aza‐Trienolate Intermediates.

Balanna, K.; Madica, K.; Mukherjee, S.; Ghosh, A.; Poisson, T.; Besset, T.; Jindal, G.; Biju, A. T.

Chem. Eur. J. 2020 , 26 , 818-822. View paper

Uncovering the Neglected Similarities of Arynes and Donor-Acceptor Cyclopropanes.

Werz, D. B.; Biju, A. T.

Angew. Chem. Int. Ed. 2020 , 59 , 3385-3398. View paper

Three-Component Aminoselenation of Arynes.

Gaykar, R. N.; Guin, A.; Bhattacharjee, S.; Biju, A. T.

Org. Lett. 2019 , 21 , 9613-9617. View paper

NHC-Catalyzed [3 + 3] Annulation of Thioamides and Modified Enals for the Enantioselective Synthesis of Functionalized Thiazinones.

Ghosh, A.; Barik, S.; Biju, A. T.

Org. Lett. 2019 , 21 , 8598-8602. View paper

[8+3]-Cycloaddition of Tropones with Azaoxyallyl Cations.

Roy, T.; Jacob, A.; Bhattacharjee, S.; Biju, A. T.

Chem. Asian. J. 2019 , 14 , 4748-4753, Invited to the Special Issue celebrating the 20th Anniversary of the CRSI. View paper

Selective Synthesis of N-H and N-Aryl Benzotriazoles by the [3+2] Annulation of Sodium Azide with Arynes.

Guin, A.; Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.

J. Org. Chem. 2019 , 84 , 12692-12699. View paper

Iodide as a Nucleophilic Trigger in Aryne Three-Component Coupling for the Synthesis of 2-Iodobenzyl Alcohols.

Bhattacharjee, S.; Guin, A.; Gaykar, R. N.; Biju, A. T.

Org. Lett. 2019 , 21 , 4383-4387, Highlighted in Organic Chemistry Portal. View paper

N-Heterocyclic Carbene-Catalyzed Umpolung of Imines for the Enantioselective Synthesis of Dihydroquinoxalines.

Das, T. K.; Ghosh, A.; Balanna, K.; Gonnade, R. G.; Marelli, U. K.; Das, A. K.; Biju, A. T.

ACS Catal. 2019 , 9 , 4065-4071, Highlighted in Org. Chem. Front. 2019, 6, 3821.. View paper

The aryne Sommelet-Hauser Rearrangement.

Roy, T.; Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.

Chem. Commun. 2019 , 55 , 3004-3007. View paper

NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles.

Mondal, S.; Yetra, S. R.; Mukherjee, S.; Biju, A. T.

Acc. Chem. Res. 2019 , 52 , 425-436. View paper

Transition-Metal-Free Thioamination of Arynes Using Sulfenamides.

Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.

Org. Lett. 2019 , 21 , 737-740. View paper

Synthesis of 2-Aryl Naphthoquinones by the Cross-Dehydrogenative Coupling Involving NHC-Catalyzed endo- Stetter Reaction.

Ghosh, A.; Patra, A.; Mukherjee, S.; Biju, A. T.

J. Org. Chem. 2019 , 84 , 1103-1110. View paper

N-Heterocyclic Carbene (NHC)-Catalyzed Transformations for the Synthesis of Heterocycles.

Progress in Heterocyclic Chemistry 2019 , Chapter 1, Editors: G. Gribble, J. Joule; ISBN: 9780128199626 , 31, Pages 1-82. View paper

N-Heterocyclic Carbene-Catalyzed Stetter Reactions and Related Chemistry.

Mondal, S.; Biju, A. T.

In N-Heterocyclic Carbenes in Organocatalysis. Wiley-VCH 2019 , Chapter 4, Editor: A. T. Biju, 2019, ISBN: 978-3-527-34310-2 , pages 53-93. View paper

Enantioselective NHC-Catalyzed Cascade Reaction for the Synthesis of Pyrroloquinolines via N-H Functionalization of Indoles.

Mukherjee, M.; Shee, S.; Poisson, T.; Besset, T.; Biju, A. T.

Org. Lett. 2018 , 20 , 6998-7002. View paper

Oxidative NHC-Catalysis for the Generation of Imidoyl Azoliums: Synthesis of Benzoxazoles.

Patra, A.; James, A.; Das, T. K.; Biju, A. T.

J. Org. Chem. 2018 , 83 , 14820-14826. View paper

N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Spiro-glutarimides via α,β-Unsaturated Acylazoliums.

Mondal, S.; Ghosh, A.; Mukherjee, S.; Biju, A. T.

Org. Lett. 2018 , 20 , 4499-4503. View paper

Recent Advances in Organocatalytic Enantioselective Synthesis of Functionalized β-Lactones.

Mukherjee, S.; Biju, A. T.

Chem. Asian J. 2018 , 13 , 2333-2349, Invited to the special issue on Homogeneous Catalysis from Young Investigators in Asia. View paper

Employing Arynes for the Generation of Aryl Anion Equivalents and Subsequent Reaction with Aldehydes.

Gaykar, R. N.; Bhunia, A.; Biju, A. T.

J. Org. Chem. 2018 , 83 , 11333-11340. View paper

N-Heterocyclic Carbene-Catalyzed Synthesis of α-Trifluoromethyl Esters.

Gelat, F.; Patra, A.; Pannecoucke, X.; Biju, A. T.; Poisson, T.; Besset, T.

Org. Lett. 2018 , 20 , 3897-3901. View paper

Trifluoromethylthiolation of α-Chloroaldehydes: An Access to Quaternary SCF3-containing Centers.

Gelat, F.; Poisson, T.; Biju, A. T. Pannecoucke, X.; Besset, T.

Eur. J. Org. Chem. 2018 , 3693-3696, Invited to the special issue Eur. J. Org. Chem.. View paper

N-Heterocyclic Carbene-Catalyzed Michael–Michael–Lactonization Cascade for the Enantioselective Synthesis of Tricyclic δ-Lactones.

Mukherjee, S.; Ghosh, A.; Marelli, U. K.; Biju, A. T.

Org. Lett. 2018 , 20 , 2952-2955. View paper

Recent Advances in Molecular Rearrangements Involving Aryne Intermediates.

Roy, T.; Biju, A. T.

Chem. Commun. 2018 , 54 , 2580-2594. View paper

Synthesis of 4-Difluoromethylquinolines by NHC-Catalyzed Umpolung of Imines.

Patra, A.; Gelat, F.; Pannecoucke, X.; Poisson, T.; Besset. T.; Biju, A. T.

Org. Lett. 2018 , 20 , 1086-1089. View paper

Base-Free and Catalyst-Free Synthesis of Functionalized Dihydrobenzoxazoles via Vinylogous Carbonate to Carbamate Rearrangement.

Das, T. K.; Mondal, S.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2017 , 19 , 5597-5600. View paper

Metal-Free, Brønsted Acid-Catalyzed Formal [3+2] Annulation of Quinone Monoacetals with 2-Naphthols.

Jacob, A.; Roy, T.; Kaicharla, T.; Biju, A. T.

J. Org. Chem. 2017 , 82 , 11269-11274. View paper

Enantioselective Synthesis of Functionalized β-Lactones by NHC-Catalyzed Aldol Lactonization of Ketoacids.

Mondal, S.; Mukherjee, S.; Das, T. K.; Gonnade, R. G.; Biju, A. T.

J. Org. Chem. 2017 , 82 , 9223-9228. View paper

Organocatalytic Enantioselective Vinylogous Michael-Aldol Cascade for the Synthesis of Spirocyclic Compounds.

Mondal, S.; Mukherjee, S.; Yetra, S. R.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2017 , 19 , 4367-4370. View paper

A Method for the Analysis of Free Carbenes Present after the NHC-Organocatalytic Transformation.

Das, T. K.; Biju, A. T.

Eur. J. Org. Chem. 2017 , 2017 , 4500-4506. View paper

AgOTf-Catalyzed Dehydrative [3+2] Annulation of Aziridines with 2-Naphthols.

Kaicharla, T.; Jacob, A.; Gonnade, R. G.; Biju, A. T.

Chem. Commun. 2017 , 53 , 8219-8222. View paper

N-Heterocyclic Carbene-Catalyzed Aldol-Lactonization of Ketoacids via Dynamic Kinetic Resolution.

Mondal, S.; Mukherjee, S.; Das, T. K.; Gonnade, R. G.; Biju, A. T.

ACS Catal 2017 , 7 , 3995-3999. View paper

Synthesis of Functionalized β-Keto Arythioethers by the Aryne Induced [2,3] Stevens Rearrangement of Allylthioethers.

Thangaraj, M.; Gaykar, R. N.; Roy, T.; Biju, A. T.

J. Org. Chem. 2017 , 82 , 4470-4476. View paper

Enantioselective Synthesis of Spiro γ-Butyrolactones by NHC-Catalyzed formal [3+2] Annulation of Enals with Dioxindoles.

Mukherjee, S.; Joseph, S.; Bhunia, A.; Gonnade R. G.; Yetra, S. R.*; Biju. A. T.

Org. Biomol. Chem. 2017 , 16 , 2013-2019. View paper

N-Heterocyclic Carbene-Catalyzed Umpolung of Imines.

Patra, A.; Mukherjee, S.; Das, T. K.; Jain, S.; Gonnade, R. G.; Biju, A. T.

Angew. Chem. Int. Ed. 2017 , 56 , 2730-2734. View paper

Facile Synthesis of N-Acyl 2-Aminobenzothiazoles by NHC-Catalyzed Direct Oxidative Amidation of Aldehydes.

Premaletha, S.; Ghosh, A.; Joseph, S.; Yetra, S. R.*; Biju, A. T.*

Chem. Commun. 2017 , 53 , 1478-1481. View paper

Substrate-Controlled Selectivity Switch in the Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and CO2.

Bhojgude, S. S.; Roy, T.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2016 , 18 , 5424-5427. View paper

The Aryne [2,3] Stevens Rearrangement.

Roy, T.; Thangaraj, M.; Kaicharla, T.; Kamath, R. V.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2016 , 18 , 5428-5431. View paper

Selective Synthesis of N-Unsubstituted and N-Aryl Indoles by the Reaction of Arynes with Azirines.

Thangaraj, M.; Bhojgude, S. S.; Gonnade, R. G.; Biju, A. T.

J. Org. Chem. 2016 , 81 , 8604-8611. View paper

Employing Arynes in Transition-Metal-Free Carbon-Carbon and Carbon-Heteroatom Bond-Forming Reactions.

Bhojgude, S. S.; Bhunia, A.; Biju, A. T.

Acc. Chem. Res. 2016 , 49 , 1658-1670. View paper

Lewis Acid-Catalyzed Selective Reactions of Donor-Acceptor Cyclopropanes with 2-Naphthols.

Kaicharla, T.; Roy, T.; Thangaraj, M.; Gonnade, R. G.; Biju, A. T.

Angew. Chem. Int. Ed. 2016 , 55 , 10215-10218. View paper

Synthesis of 4H-Chromenes by an Unexpected, Catalyst-Free, K3PO4-Mediated Intramolecular Rauhut-Currier Reaction.

Bhunia, A.; Yetra, S. R.; Gonnade, R. G.; Biju, A. T.

Org. Biomol. Chem. 2016 , 15 , 5612-5616, Invited to the "New Talent" Themed issue of OBC. View paper

Synthesis of functionalized amino epoxides by a three-component coupling involving aziridines, arynes and aldehydes.

Roy, T.; Thangaraj, M.; Gonnade. R. G.; Biju, A. T.

Chem. Commun. 2016 , 52 , 9044-9047, Invited to the Emerging Investigators-2016 Themed issue of Chem. Comm. View paper

Recent advances in N-heterocyclic carbene (NHC)-catalyzed benzoin reactions.

Menon R. S.; Biju A. T.; Nair V.

Beilstein J. Org. Chem. 2016 , 12 , 444-461. View paper

From Insertion to Multicomponent Coupling: Temperature Dependent Reactions of Arynes with Aliphatic Alcohols.

Thangaraj, M.; Bhojgude, S. S.; Biju, A. T.

Chem. Commun. 2016 , 52 , 1665-1668. View paper

Employing Carboxylic Acids in Aryne Multicomponent Coupling Triggered by Aziridines.

Roy, T.; Kaicharla, T.; Bhojgude, S. S.; Thangaraj, M.; Gonnade, R. G.; Biju, A. T.

Org. Chem. Front. 2016 , 3 , 71-76, Invited to the Emerging Investigators-2015 Themed issue of OCF. View paper

Enantioselective Synthesis of Spirocyclohexadienones by NHC-Catalyzed Formal [3+3] Annulation Reaction of Enals.

Yetra, S. R.; Mondal, S.; Mukherjee, S.; Gonnade. R. G.; Biju, A. T.

Angew. Chem. Int. Ed. 2016 , 55 , 276-280. View paper

Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and Aldehydes via Aryl–Aryl Amino Group Migration.

Bhojgude, S. S.; Baviskar, D. R.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2015 , 17 , 6270-6273. View paper

Synthesis of N-Aryl β-Amino Alcohols by Trifluoroacetic Acid-Promoted Three-Component Coupling of Aziridines, Arynes and H2O.

Roy, T. Baviskar, D. R.; Biju, A. T.

J. Org. Chem. 2015 , 80 , 11131-11137. View paper

Diastereoselective synthesis of cyclopentanone-fused spirooxindoles by N-heterocyclic carbene-catalyzed homoenolate annulation with isatilidenes.

Patra, A.; Bhunia, A.; Yetra, S. R.; Gonnade. R. G.; Biju, A. T.

Org. Chem. Front. 2015 , 2 , 1584-1588, Invited to the Carbenes for Today themed issue of OCF. View paper

Reaction of N-Heterocyclic Carbenes with Chalcones Leading to the Synthesis of Deoxy-Breslow Intermediates in their Oxidized Form.

Bhunia, A.; Thorat, S.; Gonnade, R. G.; Biju, A. T.

Chem. Commun. 2015 , 51 , 13690-13693. View paper

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions.

Menon, R. S.; Biju, A. T. Nair, V.

Chem. Soc. Rev. 2015 , 44 , 5040-5052. View paper

N-Heterocyclic Carbene-Catalyzed Diastereoselective Synthesis of -Lactone-fused Cyclopentanes Using Homoenolate Annulation Reaction.

Mukherjee, S.; Mondal, S.; Patra, A.; Gonnade, R. G.; Biju, A. T.

Chem. Commun. 2015 , 51 , 9559-9562, Highlighted in Organic Chemistry Portal. View paper

Enantioselective Synthesis of Functionalized Pyrazoles by NHC-Catalyzed Reaction of Pyrazolones with α,β-Unsaturated Aldehydes.

Yetra, S. R.; Mondal, S.; Suresh, E. Biju, A. T.

Org. Lett. 2015 , 17 , 1417-1420. View paper

Recent Advances in the N-Heterocyclic Carbene (NHC)-Catalyzed Stetter Reaction and Related Chemistry.

Yetra, S. R.; Patra, A. Biju, A. T.

Synthesis. 2015 , 47 , 1357-1378, Invited Review. View paper

NHC-Catalyzed Enantioselective Synthesis of Functionalized Cyclopentenes via α,β-Unsaturated Acyl Azoliums.

Mondal, S.; Yetra, S. R.; Patra, A.; Kunte, S. S.; Gonnade, R. G.; Biju, A. T.

Chem. Commun. 2014 , 50 , 14539-14542, Highlighted in Organic Chemistry Portal.. View paper

Rapid Access to Benzoxaphospholes and Their Spiro Analogues by a Three-Component Coupling Involving Arynes, Phosphines, and Activated Ketones.

Bhunia, A.; Roy, T.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2014 , 16 , 5132-5135. View paper

Facile Synthesis of γ-Ketophosphonates by an Intermolecular Stetter Reaction onto Vinylphosphonates.

Patra, A.; Bhunia, A.; Biju, A. T.

Org. Lett. 2014 , 16 , 4798-4801. View paper

Multicomponent Reactions Involving Phosphines, Arynes and Aldehydes.

Bhunia, A.; Kaicharla, T.; Porwal, D. Gonnade, R. G.; Biju, A. T.

Chem. Commun. 2014 , 50 , 11389-11392. View paper

Tandem [4 + 2]/[2 + 2] Cycloaddition Reactions Involving Indene or Benzofurans and Arynes.

Bhojgude, S. S.; Thangaraj, M.; Suresh, E.; Biju, A. T.

Org. Lett. 2014 , 16 , 3576-3579. View paper

Diels-Alder Reaction of Tropones with Arynes: Synthesis of Functionalized Benzocycloheptenones.

Thangaraj, M.; Bhojgude, S. S.; Bisht, R. H.; Gonnade, R. G.; Biju, A. T.

J. Org. Chem. 2014 , 79 , 4757-4762. View paper

N-Heterocyclic Carbene-Catalyzed Reaction of 2-bromoenals with Heterocyclic C-H-Acids via -Unsaturated Acyl Azoliums.

Yetra, S. R.; Roy, T.; Bhunia, A.; Porwal, D.; Biju, A. T.

J. Org. Chem. 2014 , 79 , 4245-4251. View paper

Practical Synthesis of Phthalimides and Benzamides by a Multicomponent Reaction Involving Arynes, Isocyanides and CO2/H2O.

Kaicharla, T.; Thangaraj, M.; Biju, A. T.

Org. Lett. 2014 , 16 , 1728-1731. View paper

Efficient Synthesis of 9-Aryl Dihydrophenanthrenes: Diels-Alder/Ene Reaction Cascade Involving Arynes and Styrenes.

Bhojgude, S. S.; Bhunia, A.; Gonnade, R. G.; Biju, A. T.

Org. Lett. 2014 , 16 , 676-679. View paper

Employing Arynes in Transition-Metal-Free, N-Heterocycles Initiated Multicomponent Reactions.

Bhunia, A.; Biju, A. T.

Synlett. 2014 , 25 , 608-614, Invited Synpacts Article. View paper

Transition-Metal-Free Synthesis of Five and Six-Membered Heterocycles Employing Arynes.

Kaicharla, T.; Biju, A. T.

In Green Synthetic Approaches for Biologically Relevant Heterocycles, ELSEVIER SCIENCE, 2014 , Pages 45-76. View paper

Employing Arynes in Transition-Metal-Free, Monoarylation of Aromatic Tertiary Amines.

Bhojgude, S. S.; Kaicharla, T.; Biju, A. T.

Org. Lett. 2013 , 15 , 5452-5455. View paper

Asymmetric NHC-Catalyzed Annulation of Modified Enals with Enolizable Aldehydes.

Yetra, S. R.; Kaicharla, T.; Kunte, S. S.; Gonnade, R.; Biju, A. T.

Org. Lett. 2013 , 15 , 5202-5205. View paper

Multicomponent Reactions Involving Arynes, Quinolines and Aldehydes.

Bhunia, A.; Porwal, D.; Gonnade, R.; Biju, A. T.

Org. Lett. 2013 , 15 , 4620-4623. View paper

Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles and Isatins.

Bhunia, A.; Roy, T.; Pachfule, P.; Rajamohanan, P. R.; Biju, A. T.

Angew. Chem. Int. Ed. 2013 , 52 , 10040-10044, One among the most accessed articles in August 2013, Invited for Synpacts.. View paper

Engaging isatins in solvent-free, sterically congested Passerini reaction.

Kaicharla, T.; Yetra, S. R.; Roy, T.; Biju, A. T.

Green Chem. 2013 , 15 , 1608-1614. View paper

NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones: Diastereoselective Synthesis of Functionalized Coumarins.

Bhunia, A.; Patra, A.; Puranik, V.; Biju, A. T.

Org. Lett. 2013 , 15 , 1756-1759, This work has been Highlighted in Synfacts 2013, 9, 670. View paper

Enantioselective N-Heterocyclic Carbene-Catalyzed Annulations of 2-Bromoenals with 1,3-Dicarbonyl Compounds and Enamines via Chiral α,β-Unsaturated Acyl Azoliums.

Yetra, S. R.; Bhunia, A.; Patra, A.; Mane, M. V.; Vanka, K.; Biju, A. T.

Adv. Synth. Catal. 2013 , 355 , 1089-1097. View paper

Efficient Diels-Alder Reaction of 1,2-Benzoquinones with Arynes and Its Utility in One-Pot Reactions.

Kaicharla, T.; Bhojgude, S. S.; Biju, A. T.

Org. Lett. 2012 , 14 , 6238-6241. View paper

A Practical and General Diels-Alder Reaction of Pentafulvenes with Arynes.

Bhojgude, S. S.; Kaicharla, T.; Bhunia, A.; Biju, A. T.

Org. Lett. 2012 , 14 , 4098-4101. View paper

Efficient Synthesis of γ-Keto Sulfones by NHC-Catalyzed Intermolecular Stetter Reaction.

Bhunia, A.; Yetra, S. R.; Bhojgude, S. S.; Biju, A. T.

Org. Lett. 2012 , 14 , 2830-2833. View paper

Recent Advances in Transition-Metal-Free Carbon-Carbon and Carbon-Heteroatom Bond-Forming Reactions Using Arynes.

Bhunia, A.; Yetra, S. R.; Biju, A. T.

Chem. Soc. Rev. 2012 , 41 , 3140-3152. View paper

Arynes in Transition-Metal-Free Multicomponent Coupling Reactions.

Bhojgude, S. S.; Biju, A. T.

Angew. Chem. Int. Ed. 2012 , 51 , 1520-1522. View paper

1,2-Benzoquinones in Diels-Alder Reactions, Dipolar Cycloadditions, Nucleophilic Additions, Multicomponent Reactions and more.

Nair, V.; Menon, R. S.; Biju, A. T.; Abhilash, K. G.

Chem. Soc. Rev. 2012 , 41 , 1050-1059. View paper

Organocatalytic Asymmetric 1,6-Addition Reactions.

Biju, A. T.

ChemCatChem. 2011 , 3 , 1847-1849. View paper

Efficient Synthesis of Benzofuranones: N-Heterocyclic Carbene (NHC)/Base-Catalyzed Hydroacylation-Stetter-Rearrangement Cascade.

Padmanaban, M.; Biju, A. T.; Glorius, F.

Org. Lett. 2011 , 13 , 5624-5627. View paper

Employing Homoenolates Generated by NHC Catalysis in Carbon-Carbon Bond-Forming Reactions: State of the Art.

Nair, V.; Menon, R. S.; Biju, A. T.; Sinu, C. R.; Paul, R. R.; Jose, A.; Sreekumar, V.

Chem. Soc. Rev. 2011 , 40 , 5336-5346. View paper

N-Heterocyclic Carbene (NHC)-Catalyzed Umpolung of Michael Acceptors for Intermolecular Reactions.

Biju, A. T.; Padmanaban, M.; Wurz, N. E.; Glorius, F.

Angew. Chem. Int. Ed. 2011 , 50 , 8412-8415. View paper

Extending NHC-Catalysis: Reaction of Aldehydes with Unconventional Reaction Partners.

Biju, A. T.; Kuhl, N. Glorius, F.

Acc. Chem. Res. 2011 , 44 , 1182-1195. View paper

Synthesis and Application of a Chiral Diborate.

Loewer, Y.; Weiss, C.; Biju, A. T.; Fröhlich, R.; Glorius, F.

J. Org. Chem. 2011 , 76 , 2324-2327.

N-Heterocyclic Carbene-Catalyzed Cross-Coupling of Aromatic Aldehydes with Activated Alkyl Halides.

Padmanaban, M.; Biju, A. T.; Glorius, F.

Org. Lett. 2011 , 13 , 98-101, This work has been Highlighted in Synfacts 2011, 2, 209..

Intermolecular N-Heterocyclic Carbene-Catalyzed Hydroacylation of Arynes.

Biju, A. T.; Glorius, F.

Angew. Chem. Int. Ed. 2010 , 49 , 9761-9764, This Communication is one of the most accessed papers in November 2010, Selected as Hot Paper by Angewandte Chemie, This work has been Highlighted in Synfacts 2011, 1, 95.. View paper

N-Heterocyclic Carbene-Catalyzed Cascade Reaction Involving the Hydroacylation of Unactivated Alkynes.

Biju, A. T.; Wurz, N. E.; Glorius, F.

J. Am. Chem. Soc. 2010 , 132 , 5970-5971, This work has been Highlighted in Synfacts 2010, 6, 716..

Switching the Electron-Donor Properties of N-Heterocyclic Carbenes by a Facile Deprotonation Strategy.

Biju, A. T.; Hirano, K.; Fröhlich, R.; Glorius, F.

Chem. Asian J. 2009 , 4 , 1786-1789.

Copper-Catalyzed Synthesis of 2-Unsubstituted, N-Substituted Benzimidazoles.

Hirano, K.; Biju, A. T.; Glorius, F.

J. Org. Chem. 2009 , 74 , 9570-9572.

N-Heterocyclic Carbene-Catalyzed Hydroacylation of Unactivated Double Bonds.

Hirano, K.†; Biju, A.T.† ; Piel, I.; Glorius, F.

J. Am. Chem. Soc. 2009 , 131 , 14190-14191.

Polymeric Ladderphanes.

Chou, C.-M.; Lee, S.-L.; Chen, C.-H; Biju, A. T.; Wang, H.-W.; Wu, Y.-L.; Zhang, G.-F.; Yang, K.-W.; Lim, T.-S.; Huang, M.-J.; Tsai, P.-Y.; Lin, K.-C.; Huang, S.-L.; Chen, C.-H.; Luh, T.-Y.

J. Am. Chem. Soc. 2009 , 131 , 12579-12585.

Reactions of Morita-Baylis-Hillman Acetates with Huisgen Zwitterions: A Novel Strategy for the Synthesis of β-Amino Acid Derivatives.

Jose, A.; Paul, R. R.; Mohan, R.; Mathew, S. C.; Biju, A. T.; Suresh, E.; Nair, V.

Synthesis, 2009 , 1829-1833. View paper

Carbon-Nitrogen Bond-Forming Reactions of Dialkyl Azodicarboxylate: A Promising Synthetic Strategy.

Nair, V.; Biju, A. T.; Mathew, S. C.; Beneesh, P. B.

Chem. Asian J. 2008 , 3 , 810-820. View paper

Reaction of Huisgen Zwitterion with Diaryl Ketones Leading to the Facile Synthesis of Mono- and Bis(alkoxycarbonyl)hydrazones.

Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.

Synthesis, 2008 , 1078-1084. View paper

Reaction of TPP-Azodicarboxylate Zwitterions and Aldehydes: Unprecedented Synthesis of Acyl Carbamates.

Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.

Tetrahedron Lett. 2007 , 48 , 9018-9020.

Efficient Higher-Order Cycloaddition Reactions of 8,8-Dicyanoheptafulvenes with Dienes.

Nair, V.; Abhilash, K. G.; Biju, A. T.; Suresh, E.

Synthesis, 2007 , 8 , 1833-1836. View paper

Stereoselective Synthesis of 3,4-trans-Disubstituted γ-Lactams by Cerium(IV) Ammonium Nitrate Mediated Radical Cyclization of Cinnamamides.

Nair, V.; Mohanan, K.; Suja, T. D.; Biju, A. T.

Synthesis, 2007 , 8 , 1179-1184. View paper

A Novel Reaction of the “Huisgen Zwitterion” with Chalcones and Dienones: An Efficient Strategy for the Synthesis of Pyrazoline and Pyrazolopyridazine Derivatives.

Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.

Angew. Chem. Int. Ed. 2007 , 46 , 2116-2119, This work has been Highlighted in Synfacts 2007, 577.. View paper

The Reaction of Huisgen Zwitterion with Diaryl-1,2-diones and Ketones: An Efficient Protocol for Carbon-Nitrogen Bond Formation.

Nair, V.; Biju, A. T.; Mathew, S. C.

Synthesis, 2007 , 2007 , 697-704. View paper

DMAP-Catalyzed Reaction of -ketoesters and Dimethyl Acetylenedicarboxylate: An Efficient Synthesis of Polysubstituted Benzenes and Biaryls.

Nair, V.; Vidya, N.; Biju, A. T.; Deepthi, A.; Abhilash, K. G.; Suresh, E.

Tetrahedron, 2006 , 62 , 10136-10140. View paper

Engaging Zwitterions in Carbon-Carbon and Carbon-Nitrogen Bond- Forming Reactions: A Promising Synthetic Strategy.

Nair, V.; Menon, R. S.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.

Acc. Chem. Res. 2006 , 39 , 520-530. View paper

Novel Synthesis of Highly Functionalized Pyrazolines and Pyrazoles by Triphenylphosphine Mediated Reaction of Dialkyl Azodicarboxylate with Allenic Esters.

Nair, V.; Biju, A. T.; Mohanan, K.; Suresh, E.

Org. Lett. 2006 , 8 , 2213-2216.

Reaction of Huisgen Zwitterion with 1,2-Benzoquinones and Isatins: Expeditious Synthesis of Dihydro-1,2,3-Benzoxadiazoles and Spirooxadiazolines.

Nair, V.; Biju, A. T.; Vinod, A. U.; Suresh, E.

Org. Lett. 2005 , 7 , 5139-5142.

Reaction of Diaryl-1,2-diones with Triphenylphosphine and Diethyl Azodicarboxylate Leading to N, N-Dicarboethoxy Monohydrazones via a Novel Rearrangement.

Nair, V.; Biju, A. T.; Abhilash, K. G.; Menon, R. S.; Suresh, E.

Org. Lett. 2005 , 7 , 2121-2123. View paper

1,4-Dipolar Cycloaddition in Organic synthesis: A Facile Route to Isoquinoline Fused Heterocycles.

Nair, V.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.; Varma, L.; Viji, S.; Mathew, S.

ARKIVOC 2005 , 9 , 178-188. View paper

One Pot Four Component Reaction of Isocyanides, Dimethyl Acetylenedicarboxylate and Cyclobutene-1,2-diones: Synthesis of Spiro heterocycles.

Nair, V.; Menon, R. S.; Deepthi, A.; Devi, B.R.; Biju, A. T.

Tetrahedron Lett. 2005 , 46 , 1337-1339. View paper

Novel Pyridine Catalyzed Reaction of Dimethyl Acetylenedicarboxylate with Carbonyl Compounds and N-Tosylimines: Efficient Synthesis of 2-Benzoyl Fumarates and 1-Azadienes.

Nair, V.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.; Remadevi, B.; Menon, R. S.; Rath, N. P.

Synthesis 2003 , 12 , 1895-1902. View paper

The Reaction of Isoquinoline and Dimethyl Acetylenedicarboxylate with 1,2- and 1,4-diones: A Novel Synthesis of Spiro [1,3] oxazino [2,3-a] isoquinolines.

Nair, V.; Sreekanth, A. R.; Biju, A. T.; Rath, N. P.

Tetrahedron Lett. 2003 , 44 , 729-732. View paper