2024
162. Birth of Organocatalysis by N-Heterocyclic Carbenes.
Chakraborty, S.; Biju, A. T.
Nat. Catal. 2024, 7, 1060-1062. Link. Invited Retro News & Views
160. Lewis Acid-Catalyzed (3+2) Annulation of Bicyclobutanes with Ynamides: Access to 2-Amino Bicyclo[2.1.1]hexenes.
Sarkar, D.; Deswal, S.; Das, R. C.; Biju, A. T.
Chem. Sci. 2024, 15, 16243-16249. Link.
159. Lewis Acid-Catalyzed 1,3-Dipolar Cycloaddition of Bicyclobutanes with Isatogens: Access to Indoxyl-Fused Bicyclo[3.1.1]heptanes.
Deswal, S.; Das, R. C.; Sarkar, D.; Biju, A. T.
ChemRxiv. 2024, Preprint. Link.
157. Electroredox N-Heterocyclic Carbene-Catalyzed Enantioselective (3+3) Annulation of Enals with 2-Naphthols.
Kale, V.; Shee, S.; Dutt, S.; Sinha, N.; Biju, A. T.; Banerjee, P.
ChemRxiv. 2024, Preprint. Link
154. Atroposelective Synthesis of N–N Axially Chiral Indoles and Pyrroles via NHC-Catalyzed Diastereoselective (3 + 3) Annulation Strategy.
Ranganathappa, S. S.; Dehury, B, S.; Singh, G. K.; Shee, S.; Biju, A. T.
ACS Catal. 2024, 14, 6965-6972. Link.
153. N-Heterocyclic Carbene-Catalyzed Imine Umpolung/Semipinacol Rearrangement Cascade for the Synthesis of Indoxyls.
Das, R. C.; Barik, S.; Kunhiraman, A. A.; Goswami, A.; Mondal, A.; De, M.; Biju, A. T.
ACS Catal. 2024, 14, 4202-4210. Link.
152. Enantioselective Synthesis of Tricyclic Oxoquinolines via NHC-Catalyzed Michael-Aldol-Lactamization-Dehydration Cascade.
Barik, S.; Sankar, G.; Biju, A. T.
Chem. Commun. 2024, 60, 4290-4293. Link. Featured as the Cover Page of the issue in Chem. Commun.
151. Lewis Acid-Catalyzed One-Pot Thioalkenylation of Donor-Acceptor Cyclopropanes Using in situ Generated Dithiocarbamates and Propiolates.
Harikumar, S.; Kandy, L. T. K.; Guin, A.; Biju, A. T.
Org. Biomol. Chem. 2024, 22, 1834-1838. Link. Invited to the special issue celebrating the 100th birthday of Prof. Sukh Dev.
150. Stereoselective Alder-ene Reactions of Bicyclo[1.1.0]butanes: Facile Synthesis of Cyclopropyl- and Aryl-substituted Cyclobutenes.
Dasgupta, A.; Bhattacharjee, S.; Tong, Z.; Guin, A.; McNamee, R.; Christensen, K.; Biju, A. T.; Anderson, E.
J. Am. Chem. Soc. 2024, 146, 1196-1203. Link; ChemRxiv. 2023, Preprint. Link
149. Ring-Opening 1,3-Difunctionalization of Donor-Acceptor Cyclopropanes.
Guin, A.; Biju, A. T.
In “Donor-Acceptor Cyclopropanes in Organic Synthesis“, Chapter 5, Editors: P. Banerjee and A. T. Biju; Wiley-VCH. 2024, ISBN: 978-3-527-349876, Pages 167-190. Link
2023
148. Enantioselective Synthesis of C-O Axially Chiral Diaryl Ethers via NHC-Catalyzed Atroposelective Desymmetrization.
Shee, S.; Ranganathappa, S. S.; Gadhave, M. S.; Gogoi, R.; Biju, A. T.
Angew. Chem. Int. Ed. 2023, 62, e202311709. Link; ChemRxiv. 2023, Preprint. Link
This article appears in ‘HOT Topic’: Organocatalysis Link
147. Nucleophilic Acylation-Annulation Cascade of 2-Chlorobenzonitriles using Aldehydes Triggered by N-Heterocyclic Carbenes.
Gadhave, M. S.; Barik, S.; Wessels, F.; Biju, A. T.
Org. Lett. 2023, 25, 8314-8319. Link
146. NHC-Catalyzed Enantioselective Synthesis of Tetracyclic δ-Lactones by (4 + 2) Annulation of ortho-Quinodimethanes with Activated Ketones.
Sarkar, D.; Barik, S.; Shee, S.; Biju, A. T.
Org. Lett. 2023, 25, 7852–7857. Link
144. Lewis Acid-Catalyzed Diastereoselective Carbofunctionalization of Bicyclobutanes Employing Naphthols.
Guin, A.; Bhattacharjee, S.; Harariya, M. S.; Biju, A. T.
Chem. Sci. 2023, 14, 6585-6591. Link
143. Benzotriazole-Triggered Three-Component Lewis Acid-Catalyzed Ring-Opening 1,3-Aminofunctionalization of Donor-Acceptor Cyclopropanes.
Deswal, S.; Guin, A.; Biju, A. T.
Org. Lett. 2023, 25, 1643-1648. Link
142. Directing Group-Free Regioselective meta-C-H Functionalization of Pyridines.
Chakraborty, S.; Biju, A. T.
Angew. Chem. Int. Ed. 2023, 62, e202300049. Link
141. N-Heterocyclic Carbene-Catalyzed aza-Michael-Mannich-Lactamization Cascade for the Enantioselective Synthesis of Pyrazoloquinolin-3-ones.
Shee, S.; Sarkar, D.; Biju, A. T.
Org. Lett. 2023, 25, 220-225. Link
2022
140. Enantioselective Synthesis of Dihydrothiopyranones via NHC-Catalyzed [3 + 3] Annulation of 2-Bromoenals with β-Oxodithioesters.
Barik, S.; Shee, S.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2022, 24, 8848-8853. Link
139. Dynamic Kinetic Resolution of γ,γ-Disubstituted Indole 2-Carboxaldehydes via NHC-Lewis Acid Cooperative Catalysis for the Synthesis of Tetracyclic ε-Lactones.
Balanna, K.; Barik, S.; Shee, S.; Gonnade, R. G.; Biju, A. T.
Chem. Sci. 2022, 13, 11513-11518. Link
Among the 2022 Chem.Sci. Pick of the Week Collection and 2022 Chem. Sci. HOT Article Collection
138. N-Heterocyclic Carbene-Catalyzed Umpolung of Cyclopent-4-ene-1,3-diones for Activated Olefin–Isatin Cross-Coupling.
Barik, S.; Shee, S.; Biju, A. T.
Org. Lett. 2022, 24, 6066-6071. Link
137. Kinetic Resolution Approach to the Synthesis of C-N Axially Chiral N-Aryl Aminomaleimides via NHC-Catalyzed [3+3] Annulation.
Barik, S.; Das, R. C.; Balanna, K.; Biju, A. T.
Org. Lett. 2022, 24, 5456-5461. Link
136. Synthesis of Trisubstituted Oxazoles via Aryne Induced [2,3] Sigmatropic Rearrangement-Annulation Cascade.
Gaykar, R. N.; Deswal, S.; Guin, A.; Bhattacharjee, S.; Biju, A. T.
Org. Lett. 2022, 24, 4145-4150. Link
135. N-Heterocyclic Carbene (NHC)-Catalyzed Transformations Involving Azolium Enolates.
Mondal, A.; Ghosh, A.; Biju, A. T.
Chem. Rec. 2022, 22, e202200054. Link
134. Ring-Opening 1,3-Carbothiolation of Donor-Acceptor Cyclopropanes Using Alkyl Halides and in Situ Generated Dithiocarbamates.
Guin, A.; Deswal, S.; Biju, A. T.
J. Org. Chem. 2022, 87, 6504-6513. Link
133. A Benzannulation Strategy for Rapid Access to Quinazoline-2,4-diones via Oxidative N-Heterocyclic Carbene Catalysis.
Ghosh, A.; Shee, S.; Biju, A. T.
Org. Lett. 2022, 24, 2772-2777. Link
132. Organocatalytic Routes to C-H Functionalization Reactions.
Barik, S.; Biju, A. T.
In “Handbook of C-H Functionalization (CHF)“, Editor: D. Maiti
Wiley-VCH, 2022, In Press. Link
131. Organocatalytic Umpolung Strategies – Beyond Classical Reactivity Patterns.
Shee, S.; Ghosh, A.; Biju, A. T.
In “Asymmetric Organocatalysis: New Strategies, and Opportunities“, Chapter 22, Editors: L. Albrecht, A. Albrecht, L. Dell’Amico
Wiley-VCH, 2022, In Press. Link
130. Molecular Rearrangements.
Guin, A.; Deswal, S.; Biju, A. T.
In “Comprehensive Aryne Synthetic Chemistry“, Chapter 3-4, Editor: H. Yoshida
Elsevier, 2022, Pages 223-266. Link
2021
129. Aryne Three-Component Coupling Involving CS2 for the Synthesis of S-Aryl Dithiocarbamates.
Bhattacharjee, S.; Deswal, S.; Manoj, N.; Jindal, G.; Biju, A. T.
Org. Lett. 2021, 23, 9083-9088. Link
128. Synthesis of Functionalized Dihydrocoumarins by NHC-Catalyzed [3+3] Annulation of Enals with 2-Substituted Naphthoquinones.
Shee, S.; Barik, S.; Ghosh, A.; Biju, A. T.
Org. Lett. 2021, 23, 8039-8044. Link
127. Three-Component, Diastereoselective [6+3] Annulation of Tropone, Imino Esters and Arynes.
Guin, A.; Gaykar, R. N.; Deswal, S.; Biju, A. T.
Org. Lett. 2021, 23, 7456-7461. Link
126. Transition-Metal-Free C2-Functionalization of Pyridines through Aryne Three-Component Coupling.
Guin, A.; Bhattacharjee, S.; Biju, A. T.
Chem. Eur. J. 2021, 27, 13864-13869. Link
Selected as a “Hot Paper” by the Editors
125. Enantioselective Synthesis of Tetra-substituted Tetralines and Tetra-hydroindolizines via NHC-Catalyzed Azolium-Enolate Cascade.
Ghosh, A.; Barik, S.; Shee, S.; Biju, A. T.
Chem. Commun. 2021, 57, 7794-7797. Link
124. Oxidative N-Heterocyclic Carbene (NHC) Catalysis for the Rapid Access to Functionalized Pyrrolo-oxazinones.
Ghosh, A.; Barik, S.; Barik, S.; Shee, S.; Biju, A. T.
Tetrahedron. 2021, 94, 132330. Link
Invited to the Special issue on System-Oriented Development of Organocatalysis. For details, see: Link
123. Enantioselective Synthesis of 5,6-Dihydroindolizines by N-Heterocyclic Carbene (NHC)-Catalyzed Core-Structure-Inspired Strategy of Azolium Enolate Cascade.
Ghosh, A.; Shee, S.; Barik, S.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2021, 23, 5223-5228. Link
122. An Umpolung Oxa-[2,3] Sigmatropic Rearrangement Employing Arynes for the Synthesis of Functionalized Enol Ethers.
Gaykar, R. N.; George, M.; Guin, A.; Bhattacharjee, S.; Biju, A. T.
Org. Lett. 2021, 23, 3447-3452. Link
121. NHC-Catalyzed Desymmetrization of N-Aryl Maleimides Leading to the Atroposelective Synthesis of N-Aryl Succinimides.
Barik, S.; Shee, S.; Das, S.; Gonnade, R. G.; Jindal, G.; Mukherjee, S.; Biju, A. T.
Angew. Chem. Int. Ed. 2021, 60, 12264-12268. Link
This article appears in ‘HOT Topic’: Organocatalysis Link; Highlighted in Synfacts 2021, 17, 691. Link
119. Hetarynes, Cycloalkynes and Related Intermediates.
Guin, A.; Bhattacherjee, S.; Biju, A. T.
In “Modern Aryne Chemistry“, Chapter 9, Editor: A. T. Biju; Wiley-VCH. 2021, ISBN: 978-3-527-34646-2, pages 359-406. Link
118. An Introduction to the Chemistry of Arynes.
Roy, T.; Guin, A.; Biju, A. T.
In “Modern Aryne Chemistry“, Chapter 1, Editor: A. T. Biju; Wiley-VCH. 2021, ISBN: 978-3-527-34646-2, pages 1-25. Link
117. Employing Arynes in Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles: An Update.
Roy, T.; Biju, A. T.
In “Green Synthetic Approaches for Biologically Relevant Heterocycles“, Chapter 11, Editor: G. Brahmachari;
Elsevier Science, 2021, 355-382. Link
2020
116. N-Heterocyclic Carbene (NHC) Organocatalysis Using Aliphatic Aldehydes.
Barik, S.; Biju, A. T.
Chem. Commun. 2020, 56, 15484-15495. Link
115. Thiophenols as Protic Nucleophilic Triggers in Aryne Three-Component Coupling.
Bhattacherjee, S.; Guin, A.; Gaykar, R. N.; Biju, A. T.
Org. Lett. 2020, 22, 9097-9101. Link
113. Imines as Acceptors and Donors in N-Heterocyclic Carbene (NHC) Organocatalysis.
Das, T. K.; Biju, A. T.
Chem. Commun. 2020, 56, 8537-8552. Link
Selected as a “HOT Article” by Editor & Referees of Chem. Commun. Link
112. Rapid Synthesis of Zwitterionic Phosphonium Benzoates by a Three‐Component Coupling Involving Phosphines, Arynes and CO2.
Bhattacharjee, S.; Raju, A.; Gaykar, R. N.; Gonnade, R. G.; Roy, T.; Biju, A. T.
Chem. Asian J. 2020, 15, 2203-2207. Link
This article appears in ‘HOT Topic’: Carbon Dioxide Link
111. Catalytic, Enantioselective C2-Functionalization of 3-Aminobenzofurans Using N-Heterocyclic Carbenes.
Barik, S.; Shee, S.; Ghosh, A.; Biju, A. T.
Org. Lett. 2020, 22, 3865-3869. Link
110. N-Heterocyclic Carbene Catalysis Exploiting Oxidative Imine Umpolung for the Generation of Imidoyl Azoliums.
Das, T. K.; Madica, K.; Krishnan, J.; Marelli, U. K.; Biju, A. T.
J. Org. Chem. 2020, 85, 5114-5121. Link
109. Lewis Acid-Catalyzed Ring-Opening 1,3-Aminothiolation of Donor-Acceptor Cyclopropanes Using Sulfenamides.
Guin, A.; Rathod, T.; Gaykar, R. N.; Roy, T.; Biju, A. T.
Org. Lett. 2020, 22, 2276-2280. Link
108. N-Heterocyclic Carbene-Catalyzed Formal [6+2] Annulation Reaction via Cross-Conjugated Aza-Trienolate Intermediates.
Balanna, K.; Madica, K.; Mukherjee, S.; Ghosh, A.; Poisson, T.; Besset, T.; Jindal, G.; Biju, A. T.
Chem. Eur. J. 2020, 26, 818-822. Link
This article appears in ‘HOT Topic’: Organocatalysis Link
107. Uncovering the Neglected Similarities of Arynes and Donor-Acceptor Cyclopropanes.
Werz, D. B.; Biju, A. T.
Angew. Chem. Int. Ed. 2020, 59, 3385-3398. Link
2019
106. Three-Component Aminoselenation of Arynes.
Gaykar, R. N.; Guin, A.; Bhattacharjee, S.; Biju, A. T.
Org. Lett. 2019, 21, 9613-9617. Link
105. NHC-Catalyzed [3 + 3] Annulation of Thioamides and Modified Enals for the Enantioselective Synthesis of Functionalized Thiazinones.
Ghosh, A.; Barik, S.; Biju, A. T.
Org. Lett. 2019, 21, 8598-8602. Link
104. [8+3]-Cycloaddition of Tropones with Azaoxyallyl Cations.
Roy, T.; Jacob, A.; Bhattacharjee, S.; Biju, A. T.
Chem. Asian. J. 2019, 14, 4748-4753. Link
Invited to the Special Issue celebrating the 20th Anniversary of the Chemical Research Society of India (CRSI)
103. Selective Synthesis of N-H and N-Aryl Benzotriazoles by the [3+2] Annulation of Sodium Azide with Arynes.
Guin, A.; Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.
J. Org. Chem. 2019, 84, 12692-12699. Link
102. N-Heterocyclic Carbene (NHC)-Catalyzed Transformations for the Synthesis of Heterocycles.
Das, T. K.; Biju, A. T.
Progress in Heterocyclic Chemistry 2019, 31, Pages 1-82; Chapter 1, Editors: G. Gribble, J. Joule; ISBN: 9780128199626. Link
101. Iodide as a Nucleophilic Trigger in Aryne Three-Component Coupling for the Synthesis of 2-Iodobenzyl Alcohols.
Bhattacharjee, S.; Guin, A.; Gaykar, R. N.; Biju, A. T.
Org. Lett. 2019, 21, 4383-4387. Link
Highlighted in Organic Chemistry Portal
100. N-Heterocyclic Carbene-Catalyzed Umpolung of Imines for the Enantioselective Synthesis of Dihydroquinoxalines.
Das, T. K.; Ghosh, A.; Balanna, K.; Behera, P.; Gonnade, R. G.; Marelli, U. K.; Das, A. K.; Biju, A. T.
ACS Catal. 2019, 9, 4065-4071. Link
Highlighted in Org. Chem. Front. 2019, 6, 3821. Link
99. The aryne Sommelet-Hauser rearrangement.
Roy, T.; Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.
Chem. Commun. 2019, 55, 3004-3007. Link
98. NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles.
Mondal, S.; Yetra, S. R.; Mukherjee, S.; Biju, A. T.
Acc. Chem. Res. 2019, 52, 425-436. Link
97. Transition-Metal-Free Thioamination of Arynes Using Sulfenamides.
Gaykar, R. N.; Bhattacharjee, S.; Biju, A. T.
Org. Lett. 2019, 21, 737-740. Link
96. Synthesis of 2-Aryl Naphthoquinones by the Cross-Dehydrogenative Coupling Involving NHC-Catalyzed endo-Stetter Reaction.
Ghosh, A.; Patra, A.; Mukherjee, S.; Biju, A. T.
J. Org. Chem. 2019, 84, 1103-1110. Link
95. N-Heterocyclic Carbene-Catalyzed Stetter Reaction and Related Chemistry.
Mondal, S.; Yetra, S. R.; Biju, A. T.
In “N-Heterocyclic Carbenes in Organocatalysis“, Chapter 4, Editor: A. T. Biju
Wiley-VCH, 2019, ISBN: 978-3-527-34310-2, pages 53-93. Link
2018
94. Enantioselective N-Heterocyclic Carbene-Catalyzed Cascade Reaction for the Synthesis of Pyrroloquinolines via N–H Functionalization of Indoles.
Mukherjee, S.; Shee, S.; Poisson, T.; Besset, T.; Biju, A. T.
Org. Lett. 2018, 20, 6998-7002. Link
93. Oxidative NHC-Catalysis for the Generation of Imidoyl Azoliums: Synthesis of Benzoxazoles.
Patra, A.; James, A.; Das, T. K.; Biju, A. T.
J. Org. Chem. 2018, 83, 14820-14826. Link
92. N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Spiro-glutarimides via α,β-Unsaturated Acylazoliums.
Mondal, S.; Ghosh, A.; Mukherjee, S.; Biju, A. T.
Org. Lett. 2018, 20, 4499-4503. Link
91. Recent Advances in Organocatalytic Enantioselective Synthesis of Functionalized β-Lactones.
Mukherjee, S.; Biju, A. T.
Chem. Asian J. 2018, 13, 2333-2349. Link
Invited to the special issue on Homogeneous Catalysis from Young Investigators in Asia
90. Employing Arynes for the Generation of Aryl Anion Equivalents and Subsequent Reaction with Aldehydes.
Gaykar, R. N.; Bhunia, A.; Biju, A. T.
J. Org. Chem. 2018, 83, 11333-11340. Link
89. N-Heterocyclic Carbene-Catalyzed Synthesis of α-Trifluoromethyl Esters.
Gelat, F.; Patra, A.; Pannecoucke, X.; Biju, A. T.; Poisson, T.; Besset, T.
Org. Lett. 2018, 20, 3897-3901. Link
88. Trifluoromethylthiolation of α‐Chloroaldehydes: Access to Quaternary SCF3‐Containing Centers.
Gelat, F.; Poisson, T.; Biju, A. T.; Pannecoucke, X.; Besset, T.
Eur. J. Org. Chem. 2018, 3693-3696. Link
87. N-Heterocyclic Carbene-Catalyzed Michael–Michael–Lactonization Cascade for the Enantioselective Synthesis of Tricyclic δ-Lactones.
Mukherjee, S.; Ghosh, A.; Marelli, U. K.; Biju, A. T.
Org. Lett. 2018, 20, 2952-2955. Link
86. Recent Advances in Molecular Rearrangements Involving Aryne Intermediates.
Roy, T.; Biju, A. T.
Chem. Commun. 2018, 54, 2580-2594. Link
85. Synthesis of 4-Difluoromethylquinolines by NHC-Catalyzed Umpolung of Imines.
Patra, A.; Gelat, F.; Pannecoucke, X.; Poisson, T.; Besset. T.; Biju, A. T.
Org. Lett. 2018, 20, 1086-1089. Link
2017
84. Base-Free and Catalyst-Free Synthesis of Functionalized Dihydrobenzoxazoles via Vinylogous Carbonate to Carbamate Rearrangement.
Das, T. K.; Mondal, S.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2017, 19, 5597-5600. Link
83. Metal-Free, Brønsted Acid-Catalyzed Formal [3+2] Annulation of Quinone Monoacetals with 2-Naphthols.
Jacob, A.; Roy, T.; Kaicharla, T.; Biju, A. T.
J. Org. Chem. 2017, 82, 11269–11274. Link
82. Enantioselective Synthesis of Functionalized β-Lactones by NHC-Catalyzed Aldol Lactonization of Ketoacids.
Mondal, S.; Mukherjee, S.; Das, T. K.; Gonnade, R. G.; Biju, A. T.
J. Org. Chem. 2017, 82, 9223-9228. Link
81. Organocatalytic Enantioselective Vinylogous Michael-Aldol Cascade for the Synthesis of Spirocyclic Compounds.
Mondal, S.; Mukherjee, S.; Yetra, S. R.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2017, 19, 4367–4370. Link
80. A Method for the Analysis of Free Carbenes Present after the NHC-Organocatalytic Transformation.
Das, T. K.; Biju, A. T.
Eur. J. Org. Chem. 2017, 4500-4506. Link
Invited to the special issue featuring articles by emerging investigators from India
79. AgOTf-Catalyzed Dehydrative [3+2] Annulation of Aziridines with 2-Naphthols.
Kaicharla, T.; Jacob, A.; Gonnade, R. G.; Biju, A. T.
Chem. Commun. 2017, 53, 8219-8222. Link
78. N-Heterocyclic Carbene-Catalyzed Aldol-Lactonization of Ketoacids via Dynamic Kinetic Resolution.
Mondal, S.; Mukherjee, S.; Das, T. K.; Gonnade, R. G.; Biju, A. T.
ACS. Catal. 2017, 7, 3995-3999. Link
Highlighted in Organic Chemistry Portal
77. Synthesis of Functionalized Beta-Keto Arylthioethers by the Aryne Induced [2,3] Stevens Rearrangement of Allylthioethers.
Thangaraj, M.; Gaykar, R. N.; Roy, T.; Biju, A. T.
J. Org. Chem. 2017, 82, 4470–4476. Link
Highlighted in Synfacts 2017, 13, 643
76. Enantioselective Synthesis of Spiro Gamma-butyrolactones by N-Heterocyclic Carbene (NHC)-Catalyzed Formal [3+2] Annulation of Enals with 3-Hydroxy Oxindoles.
Mukherjee, S.; Joseph, S.; Bhunia, A.; Gonnade, R. G.; Yetra, S. R.; Biju, A. T.
Org. Biomol. Chem. 2017, 16, 2013-2019. Link
75. N-Heterocyclic Carbene-Catalyzed Umpolung of Imines
Patra, A.; Mukherjee, S.; Das, T. K.; Jain, S.; Gonnade, R. G.; Biju, A. T.
Angew. Chem. Int. Ed. 2017, 56, 2730- 2734. Link
Highlighted in Synfacts 2017, 13, 466; Highlighted in Organic Chemistry Portal
74. Facile Synthesis of N-Acyl 2-Aminobenzothiazoles by NHC-Catalyzed Direct Oxidative Amidation of Aldehydes.
Premaletha, S.; Ghosh, A.; Joseph, S.; Yetra, S. R.; Biju, A. T.,
Chem. Commun. 2017, 53, 1478-1481. Link
2016
73. The Aryne [2,3] Stevens Rearrangement.
Roy, T.; Thangaraj, M.; Kaicharla, T.; Kamath, R. V.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2016, 18, 5428 – 5431 . Link
72. Substrate-Controlled Selectivity Switch in the Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and CO2.
Bhojgude, S. S.; Roy, T.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2016, 18, 5424–5427. Link
71. Employing Arynes in Diels-Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions.
Bhojgude, S. S.; Bhunia, A.; Biju, A. T.,
Acc. Chem. Res. 2016, 49, 1658–1670. Link
70. Selective Synthesis of N-Unsubstituted and N-Aryl Indoles by the Reaction of Arynes with Azirines.
Thangaraj, M.; Bhojgude, S. S.; Jain, S.; Biju, A. T.
J. Org. Chem. 2016, 81, 8604–8611. Link
69. Lewis Acid Catalyzed Selective Reactions of Donor–Acceptor Cyclopropanes with 2-Naphthols.
Kaicharla, T.; Roy, T.; Thangaraj, M.; Gonnade, R. G.; Biju, A. T.
Angew. Chem. Int. Ed. 2016, 55, 10061-10064. Link
68. Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular Rauhut-Currier type reaction.
Bhunia, A.; Yetra, S. R.; Gonnade, R. G.; Biju, A. T.
Org. Biomol. Chem. 2016, 15, 5612-5616 . Link
Invited to the “New Talent” Themed Collection of OBC
67. Synthesis of functionalized amino epoxides by a three-component coupling involving aziridines, arynes and aldehydes.
Roy, T.; Thangaraj, M.; Gonnade, R. G.; Biju, A. T.
Chem. Commun. 2016, 52, 9044-9047. Link
Selected for the “Emerging Investigators-2016” themed issue of Chem. Commun.
66. Recent Advances in N-Heterocyclic Carbene (NHC)-Catalysed Benzoin Reactions.
Menon, R. S.; Biju, A. T.; Nair, V.*
Beilstein J. Org. Chem. 2016, 12, 444-461. Link
65. From Insertion to Multicomponent Coupling: Temperature Dependent Reactions of Arynes with Aliphatic Alcohols.
Thangaraj, M.; Bhojgude, S. S.; Mane, M. V.; Biju, A. T.
Chem. Commun. 2016, 52, 1665-1668 . Link
64. Employing Carboxylic Acids in Aryne Multicomponent Coupling Triggered by Aziridines/Azetidines.
Roy, T.; Bhojgude, S. S.; Kaicharla, T.; Thangaraj, M.; Garai, B.; Biju, A. T.
Org. Chem. Front. 2016, 3, 71-76. Link
2015 “Emerging Investigators” themed collection of OCF
63. Enantioselective Synthesis of Spirocyclohexadienones by NHC-Catalyzed Formal [3+3] Annulation Reaction of Enals.
Yetra, S. R.; Mondal, S.; Mukherjee, S.; Gonnade, R. G.; Biju, A. T.
Angew. Chem. Int. Ed. 2016, 55, 268-272. Link
2015
62. Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and Aldehydes via Aryl–Aryl Amino Group Migration.
Bhojgude, S. S.; Baviskar, D. R.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2015, 17, 6270–6273. Link
61. Diastereoselective Synthesis of Cyclopentanone-fused Spirooxindoles by N-Heterocyclic Carbene-Catalyzed Homoenolate Annulation with Isatilidenes.
Patra, A.; Bhunia, A.; Yetra, S. R.; Gonnade, R. G.; Biju, A. T.
Org. Chem. Front. 2015, 2, 1584-1588. Link
Invited to the “Carbenes for Today” themed collection of OCF
60. Synthesis of N-Aryl β-Amino Alcohols by Trifluoroacetic Acid-Promoted Multicomponent Coupling of Aziridines, Arynes and Water.
Roy, T.; Baviskar, D. R.; Biju, A. T.
J. Org. Chem. 2015, 80, 11131-11137. Link
59. Reaction of N-Heterocyclic Carbenes with Chalcones Leading to the Synthesis of deoxy-Breslow Intermediates in their Oxidized Form.
Bhunia, A.; Thorat, S.; Gonnade, R. G.; Biju, A. T.
Chem. Commun. 2015, 51, 13690-13693. Link
58. Recent Advances in Employing Homoenolates Generated by N-Heterocyclic Carbene (NHC) Catalysis in Carbon–Carbon Bond-Forming Reactions.
Menon, R. S.; Biju, A. T.; Nair, V.*
Chem. Soc. Rev. 2015, 44, 5040-5052. Link
57. N-Heterocyclic Carbene-Catalyzed Diastereoselective Synthesis of β-lactone-fused Cyclopentanes Using Homoenolate Annulation Reaction.
Mukherjee, S.; Mondal, S.; Patra, A.; Gonnade, R. G.; Biju, A. T.
Chem. Commun. 2015, 51, 9559-9562. Link
Highlighted in Organic Chemistry Portal
56. Enantioselective Synthesis of Functionalized Pyrazoles by NHC-Catalyzed Reaction of Pyrazolones with α,β-Unsaturated Aldehydes.
Yetra, S. R.; Mondal, S.; Suresh, E.; Biju, A. T.
Org. Lett. 2015, 17, 1417-1420. Link
55. Recent Advances in the N-Heterocyclic Carbene (NHC)-Organocatalyzed Stetter Reaction and Related Chemistry.
Yetra, S. R.; Patra, A.; Biju, A. T.
Synthesis 2015, 47, 1357-1378. Link
Invited Review; Top 10 most popular articles in April 2015
2014
54. N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Functionalized Cyclopentenes via α,β-Unsaturated Acyl Azoliums.
Mondal, S.; Yetra, S. R.; Patra, A.; Kunte, S. S.; Gonnade ,R. G.; Biju, A. T.
Chem. Commun. 2014, 50, 14539-14542. Link
Highlighted in Organic Chemistry Portal
53. Rapid Access to Benzoxaphospholes and Their Spiro Analogues by a Three-Component Coupling Involving Arynes, Phosphines, and Activated Ketones.
Bhunia, A.; Roy, T.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2014, 16, 5132-5135. Link
52. Facile Synthesis of γ-Ketophosphonates by an Intermolecular Stetter Reaction Onto Vinylphosphonates.
Patra, A.; Bhunia, A.; Biju, A. T.
Org. Lett. 2014, 16, 4798-4801. Link
For abstracts in Organic Chemistry Portal, see: www.organic-chemistry.org/abstracts/lit4/659.shtm
51. Multicomponent Reactions Involving Phosphines, Arynes and Aldehydes.
Bhunia, A.; Kaicharla, T.; Porwal, D.; Gonnade, R. G.; Biju, A. T.
Chem. Commun. 2014, 50, 11389-11392. Link
50. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes.
Kaicharla, T.; Biju, A. T.
In “Green Synthetic Approaches for Biologically Relevant Heterocycles“, Book Chapter, Editor: Prof. Goutam Brahmachari,
Elsevier Science, 2014, 45-76. Link
49. Tandem [4 + 2]/[2 + 2] Cycloaddition Reactions Involving Indene or Benzofurans and Arynes.
Bhojgude, S. S.; Thangaraj, M.; Suresh, E.; Biju, A. T.
Org. Lett. 2014, 16, 3576-3579. Link
48. Diels-Alder Reaction of Tropones with Arynes: Synthesis of Functionalized Benzobicyclo[3.2.2]nonatrienones.
Thangaraj, M.; Bhojgude, S. S.; Bisht, R. H.; Gonnade, R. G.; Biju, A. T.
J. Org. Chem. 2014, 79, 4757-4762. Link
47. Synthesis of Functionalized Coumarins and Quinolinones by NHC-Catalyzed Annulation of Modified Enals with Heterocyclic C-H Acids.
Yetra, S. R.; Roy, T.; Bhunia, A.; Porwal, D.; Biju, A. T.
J. Org. Chem. 2014, 79, 4245-4251. Link
46. Practical Synthesis of Phthalimides and Benzamides by a Multicomponent Reaction Involving Arynes, Isocyanides, and CO2/H2O.
Kaicharla, T.; Thangaraj, M.; Biju, A. T.
Org. Lett. 2014, 16, 1728-1731. Link
For abstracts in Organic Chemistry Portal, see: http://www.organic-chemistry.org/abstracts/lit4/434.shtm
45. Efficient Synthesis of 9-Aryldihydrophenanthrenes by a Cascade Reaction Involving Arynes and Styrenes.
Bhojgude, S. S.; Bhunia, A.; Gonnade, R. G.; Biju ,A. T.
Org. Lett. 2014, 16, 676-679. Link
44. Employing Arynes in Transition-Metal-Free, N-Heterocycles Initiated Multicomponent Reactions.
Bhunia, A.; Biju, A. T.
Synlett. 2014, 25, 608-614. Link
Invited Synpacts Article
2013
43. Employing Arynes in Transition-Metal-Free Monoarylation of Aromatic Tertiary Amines.
Bhojgude, S. S.; Kaicharla, T.; Biju, A. T.
Org. Lett. 2013, 15, 5452-5455. Link
For abstracts in Organic Chemistry Portal, see: http://www.organic-chemistry.org/abstracts/lit4/224.shtm
42. Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Annulation of Modified Enals with Enolizable Aldehydes.
Yetra, S. R.; Kaicharla, T.; Kunte, S. S.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2013, 15, 5202 – 5205. Link
For abstracts in Organic Chemistry Portal, see: http://www.organic-chemistry.org/abstracts/lit4/202.shtm
41. Multicomponent Reactions Involving Arynes, Quinolines, and Aldehydes.
Bhunia, A.; Porwal, D.; Gonnade, R. G.; Biju, A. T.
Org. Lett. 2013, 15, 4620- 623. Link
40. Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles and Isatins.
Bhunia, A.; Roy, T.; Pachfule, P.; Rajamohanan, P. R.; Biju, A. T.
Angew. Chem. Int. Ed. 2013, 52, 10040-10043. Link
Among the most accessed papers in August 2013, Invited for Synpacts
39. Engaging isatins in solvent-free, sterically congested Passerini reaction.
Kaicharla, T.; Yetra, S. R.; Roy, T.; Biju, A. T.
Green Chem. 2013, 15, 1608-1614. Link
38. Enantioselective N-Heterocyclic Carbene-Catalyzed Annulations of 2-Bromoenals with 1,3-Dicarbonyl Compounds and Enamines via Chiral α,β-Unsaturated Acyl Azoliums.
Yetra, S. R.; Bhunia, A.; Patra, A.; Mane, M. V.; Vanka, K.; Biju, A. T.
Adv. Synth. Catal. 2013, 335, 1089-1097. Link
37. NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones:Diastereoselective Synthesis of Functionalized Coumarins.
Bhunia, A.; Patra, A.; Puranik, V.; Biju, A. T.
Org. Lett. 2013, 15, 1756-759. Link
Highlighted in Synfacts 2013, 9, 670.
2012
36. Efficient Diels-Alder Reaction of 1,2-Benzoquinones with Arynes and Its Utility in One-Pot Reactions.
Kaicharla, T.; Bhojgude, S. S. ; Biju, A. T.
Org. Lett. 2012, 14, 6238-6241. Link
35. A Practical and General Diels-Alder Reaction of Pentafulvenes with Arynes.
Bhojgude, S. S.; Kaicharla, T.; Bhunia, A.; Biju, A. T.
Org. Lett. 2012, 14, 4098-4101. Link
34. Efficient Synthesis of γ-Keto Sulfones by NHC-Catalyzed Intermolecular Stetter Reaction.
Bhunia, A.; Yetra, S. R.; Bhojgude, S. S.; Biju, A. T.
Org. Lett. 2012, 14, 2830-2833. Link
33. 1,2-Benzoquinones in Diels-Alder reactions, dipolar cycloadditions, nucleophilic additions, multicomponent reactions and more.
Nair, V.; Menon, R. S.; Biju, A. T.; Abhilash, K. G.
Chem. Soc. Rev. 2012, 41, 1050-1059. Link
32. Arynes in Transition-Metal-Free Multicomponent Coupling Reactions.
Bhojgude, S. S.; Biju, A. T.
Angew. Chem. Int. Ed. 2012, 51, 1520-1522. Link
31. Recent Advances in Transition-Metal-Free Carbon-Carbon and Carbon-Heteroatom Bond-Forming Reactions Using Arynes.
Bhunia, A.; Yetra, S. R.; Biju, A. T.
Chem. Soc. Rev. 2012, 41, 3140-3152. Link
2011 and prior
30. Organocatalytic Asymmetric 1,6-Addition Reactions.
Biju, A. T.
Chem. Cat. Chem. 2011, 3, 1847-1849. Link
29. Efficient Synthesis of Benzofuranones: N-Heterocyclic Carbene (NHC)/Base-Catalyzed Hydroacylation-Stetter-Rearrangement Cascade.
Padmanaban, M.; Biju, A. T.; Glorius, F.
Org. Lett. 2011, 13, 5624- 5627. Link
28. Employing Homoenolates Generated by NHC Catalysis in Carbon-Carbon Bond-Forming Reactions: State of the Art.
Nair, V.; Menon, R. S.; Biju, A. T.; Sinu, C. R.; Paul, R. R.; Jose, A.; Sreekumar, V.
Chem. Soc. Rev. 2011, 40, 5336-5346. Link
27. N-Heterocyclic Carbene (NHC)-Catalyzed Umpolung of Michael Acceptors for Intermolecular Reactions.
Biju, A. T.; Padmanaban, M.; Wurz, N. E.; Glorius, F.
Angew. Chem., Int. Ed. 2011, 50, 8412-8415. Link
26. Extending NHC-Catalysis: Reaction of Aldehydes with Unconventional Reaction Partners.
Biju, A. T.; Kuhl, N. Glorius, F.
Acc. Chem. Res. 2011, 44, 1182-1195. Link
25. Synthesis and Application of a Chiral Diborate.
Loewer, Y.; Weiß, C.; Biju, A. T.; Fröhlich, R.; Glorius. F.
J. Org. Chem. 2011, 76, 2324-2327. Link
24. N-Heterocyclic Carbene-Catalyzed Cross-Coupling of Aromatic Aldehydes with Activated Alkyl Halides.
Padmanaban, M.; Biju, A. T.; Glorius, F.
Org. Lett. 2011, 13, 98-101. Link
Highlighted in Synfacts 2011, 2, 209.
23. Intermolecular N-Heterocyclic Carbene-Catalyzed Hydroacylation of Arynes.
Biju, A. T.; Glorius, F.
Angew. Chem., Int. Ed. 2010, 49, 9761-9764. Link
(This Communication is one of the most accessed papers in November 2010).
Selected as Hot Paper by Angewandte Chemie
This work has been Highlighted in Synfacts 2011, 1, 95.
22. N-Heterocyclic Carbene-Catalyzed Cascade Reaction Involving the Hydroacylation of Unactivated Alkynes.
Biju, A. T.; Wurz, N. E.; Glorius, F.
J. Am. Chem. Soc. 2010, 132, 5970-5971. Link
(This Communication is one of the most accessed papers in April 2010).
Highlighted in Synfacts 2010, 6, 716.
21. Switching the Electron-Donor Properties of N-Heterocyclic Carbenes by a Facile Deprotonation Strategy.
Biju, A. T.; Hirano, K.; Fröhlich, R.; Glorius, F.
Chem. Asian J. 2009, 4, 1786-1789. Link
20. Copper-Catalyzed Synthesis of 2-Unsubstituted, N-Substituted Benzimidazoles.
Hirano, K.; Biju, A. T.; Glorius, F.
J. Org. Chem. 2009, 74, 9570-9572. Link
19. N-Heterocyclic Carbene-Catalyzed Hydroacylation of Unactivated Double Bonds.
Hirano, K.†; Biju, A.T.† ; Piel, I.; Glorius, F.
J. Am. Chem. Soc. 2009, 131, 14190-14191. Link
Highlighted in Synfacts 2009, 12, 1404.
18. Polymeric Ladderphanes.
Chou, C.-M.; Lee, S.-L.; Chen, C.-H; Biju, A. T.; Wang, H.-W.; Wu, Y.-L.; Zhang, G.-F.; Yang, K.-W.; Lim, T.-S.; Huang, M.-J.; Tsai, P.-Y.; Lin, K.-C.; Huang, S.-L.; Chen, C.-h.; Luh, T.-Y.
J. Am. Chem. Soc. 2009, 131, 12579-12585. Link
17. Reactions of Morita-Baylis-Hillman Acetates with Huisgen Zwitterions: A Novel Strategy for the Synthesis of β-Amino Acid Derivatives.
Jose, A.; Paul, R. R.; Mohan, R.; Mathew, S. C.; Biju, A. T.; Suresh, E.; Nair, V.
Synthesis, 2009, 1829-1833. Link
16. Carbon-Nitrogen Bond-Forming Reactions of Dialkyl Azodicarboxylate: A Promising Synthetic Strategy.
Nair, V.; Biju, A. T.; Mathew, S. C.; Beneesh, P. B.
Chem. Asian J. 2008, 3, 810-820. Link
15. Reaction of Huisgen Zwitterion with Diaryl Ketones Leading to the Facile Synthesis of Mono- and Bis(alkoxycarbonyl)hydrazones.
Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.
Synthesis 2008, 1078-1084. Link
14. Reaction of TPP-Azodicarboxylate Zwitterions and Aldehydes: Unprecedented Synthesis of Acyl Carbamates.
Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.
Tetrahedron Lett. 2007, 48, 9018-9020. Link
13. Efficient Higher-Order Cycloaddition Reactions of 8,8-Dicyanoheptafulvenes with Dienes.
Nair, V.; Abhilash, K. G.; Biju, A. T.; Suresh, E.
Synthesis 2007, 1833-1836. Link
12. Stereoselective Synthesis of 3,4-trans-Disubstituted γ-Lactams by Cerium(IV) Ammonium Nitrate Mediated Radical Cyclization of Cinnamamides.
Nair, V.; Mohanan, K.; Suja, T. D.; Biju, A. T.
Synthesis 2007, 1179-1184. Link
11. A Novel Reaction of the “Huisgen Zwitterion” with Chalcones and Dienones: An Efficient Strategy for the Synthesis of Pyrazoline and Pyrazolopyridazine Derivatives.
Nair, V.; Mathew, S. C.; Biju, A. T.; Suresh, E.
Angew. Chem. Int. Ed. 2007, 46, 2070-2073. Link
Highlighted in Synfacts 2007, 577.
10. The Reaction of Huisgen Zwitterion with Diaryl-1,2-diones and Ketones: An Efficient Protocol for Carbon-Nitrogen Bond Formation.
Nair, V.; Biju, A. T.; Mathew, S. C.
Synthesis 2007, 697-704. Link
9. DMAP-Catalyzed Reaction of b-ketoesters and Dimethyl Acetylenedicarboxylate: An Efficient Synthesis of Polysubstituted Benzenes and Biaryls.
Nair, V.; Vidya, N.; Biju, A. T.; Deepthi, A.; Abhilash, K. G.; Suresh, E.
Tetrahedron 2006, 62, 10136-10140. Link
8. Engaging Zwitterions in Carbon-Carbon and Carbon-Nitrogen Bond- Forming Reactions: A Promising Synthetic Strategy.
Nair, V.; Menon, R. S.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.
Acc. Chem. Res. 2006, 39, 520-530. Link
7. Novel Synthesis of Highly Functionalized Pyrazolines and Pyrazoles by Triphenylphosphine Mediated Reaction of Dialkyl Azodicarboxylate with Allenic Esters.
Nair, V.; Biju, A. T.; Mohanan, K.; Suresh, E.
Org. Lett. 2006, 8, 2213-2216. Link
6. Reaction of Huisgen Zwitterion with 1,2-Benzoquinones and Isatins: Expeditious Synthesis of Dihydro-1,2,3-Benzoxadiazoles and Spirooxadiazolines.
Nair, V.; Biju, A. T.; Vinod, A. U.; Suresh, E.
Org. Lett. 2005, 7, 5139.
5. Reaction of Diaryl-1,2-diones with Triphenylphosphine and Diethyl Azodicarboxylate Leading to N, N-Dicarboethoxy Monohydrazones via a Novel Rearrangement.
Nair, V.; Biju, A. T.; Abhilash, K. G.; Menon, R. S.; Suresh, E.
Org. Lett. 2005, 7, 2121.
4. 1,4-Dipolar Cycloaddition in Organic synthesis: A Facile Route to Isoquinoline Fused Heterocycles.
Nair, V.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.; Varma, L.; Viji, S.; Mathew, S.
ARKIVOC 2005, 9, 178.
3. One Pot Four Component Reaction of Isocyanides, Dimethyl Acetylenedicarboxylate and Cyclobutene-1,2-diones: Synthesis of Spiro heterocycles.
Nair, V.; Menon, R. S.; Deepthi, A.; Devi, B.R.; Biju, A. T.
Tetrahedron Lett. 2005, 46, 1337.
2. Novel Pyridine Catalyzed Reaction of Dimethyl Acetylenedicarboxylate with Carbonyl Compounds and N-Tosylimines: Efficient Synthesis of 2-Benzoyl Fumarates and 1-Azadienes.
Nair, V.; Sreekanth, A. R.; Abhilash, N.; Biju, A. T.; Remadevi, B.; Menon, R. S.; Rath, N. P.
Synthesis 2003, 1895.
1. The Reaction of Isoquinoline and Dimethyl Acetylenedicarboxylate with 1,2- and 1,4-diones : A Novel Synthesis of Spiro [1,3] oxazino [2,3-a] isoquinolines.
Nair, V.; Sreekanth, A. R.; Biju, A. T.; Rath, N. P.
Tetrahedron Lett. 2003, 44, 729.